Summary of Study ST000929
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000643. The data can be accessed directly via it's Project DOI: 10.21228/M8JT38 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000929 |
| Study Title | Metabolomics Analysis of Aqueous Humour in the Presence of Glaucoma Drainage Devices |
| Study Type | Metabolomics Evaluation of Aqueous Humor Samples from Left (treated) and Right (Control) Eyes of Rabbits. |
| Study Summary | Metabolomic experiments were carried out on aqueous humor samples provided by Ramesh Ayyala. Through this collaboration, we propose to study aqueous humor from control and experimental rabbits to better understand metabolic differences in the aqueous humor samples. |
| Institute | University of North Carolina |
| Department | Nutrition Research Institute |
| Laboratory | ERCMRC |
| Last Name | Sumner |
| First Name | Susan |
| Address | 500 Laureate Way, Kannapolis, NC, 28081, USA |
| susan_sumner@unc.edu | |
| Phone | 7042505066 |
| Submit Date | 2018-02-11 |
| Num Groups | 9 |
| Total Subjects | 56 |
| Num Males | 56 |
| Analysis Type Detail | LC-MS |
| Release Date | 2018-12-11 |
| Release Version | 1 |
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Project:
| Project ID: | PR000643 |
| Project DOI: | doi: 10.21228/M8JT38 |
| Project Title: | Metabolomics Analysis of Aqueous Humour in the Presence of Glaucoma Drainage Devices |
| Project Type: | Metabolomics of the aqueous humor of rabbits with Ahmed Glaucoma Valve implantation. |
| Project Summary: | Aqueous humor samples for metabolomics experiment were generated in the following manner: Eight adult male white rabbits were given seven days to acclimate to their environment. On day eight, an Ahmed Glaucoma Valve was implanted into the left eye of every rabbit. The un-operated right eye served as control. One rabbit was lost during the course of the study. After adequate anesthesia, aqueous humor samples were taken from both eyes of each rabbit before surgery (A samples), and at 27 (B samples), 52 (C samples) and 153 days (IV samples) after surgery. |
| Institute: | Tulane University School of Medicine |
| Department: | Ophthalmology |
| Last Name: | Ayyala |
| First Name: | Ramesh S. |
| Address: | 1430 Tulane Ave., New Orleans, LA 70112 |
| Email: | rayyala@tulane.edu |
| Phone: | 504-998-2261 |
