Summary of Study ST001194
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000806. The data can be accessed directly via it's Project DOI: 10.21228/M8H390 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001194 |
Study Title | Flavonoid study of Ginkgo leaves facing to different elevation and plant age |
Study Summary | Ginkgo biloba leaves are always resources for flavonoids pharmaceutical industry. Thus, artificial planting and industrial harvesting become the vital aspect to get higher drug yields. In this research, we performed de novo transcriptome sequencing of Ginkgo leaves coupled with high-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry analyses to obtain a comprehensive understanding of the influence of elevation and plant age on flavonoid synthesis. A total of 557,659,530 clean reads were assembled into 188,155 unigenes, of which 135,102 (71.80%) were successfully annotated in seven public databases. The differentially expressed genes analysis indicated DFR, LAR and ANR were significantly up-regulated with the increase of elevation in young Ginkgo trees leaves. With less strict saliency, the relative concentration of flavonoid derivatives with high parent ion signal intensity was likely to support this conclusion. Complex gene variations were observed with the plant age change. However, flavonoid derivatives analysis predicted the potential possibility that the rise of plant age is more likely to be detrimental to the biosynthesis of Ginkgo flavonoids in leaves. From the overall DEGs involved in flavonoid biosynthesis, DFRs seemed to show more considerable variability towards the variation of elevation and plant age. Furthermore, our research effectively expanded the functional genomic library of Ginkgo and provided a reference for artificial planting and industrial harvesting. |
Institute | Central South University, China |
Last Name | Zou |
First Name | Kai |
Address | Central South University, 932 Lushan South Road, Yuelu District, Changsha City, Hunan Province |
zoukai3412085@hotmail.com | |
Phone | +8615273119784 |
Submit Date | 2019-05-05 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2019-07-05 |
Release Version | 1 |
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Project:
Project ID: | PR000806 |
Project DOI: | doi: 10.21228/M8H390 |
Project Title: | Flavonoid study of Ginkgo leaves facing to different elevation and plant age |
Project Type: | MS quantitative analysis |
Project Summary: | Flavonoid study of Ginkgo leaves facing to different elevation and plant age |
Institute: | Central South University, China |
Department: | School of Minerals Processing and Bioengineering |
Laboratory: | Key Laboratory of the Ministry of Education |
Last Name: | Zou |
First Name: | Kai |
Address: | Central South University, 932 Lushan South Road, Yuelu District, Changsha City, Hunan Province |
Email: | zoukai3412085@hotmail.com |
Phone: | +8615273119784 |