Summary of Study ST002766

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001724. The data can be accessed directly via it's Project DOI: 10.21228/M8VM7H This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002766
Study TitleThe ECHO Cohort Exposome: First Steps using HHEAR Analysis – An Opportunity for ALL ECHO Cohorts to Contribute Type A Samples – Untargeted Analysis (GAPPS Cohort)
Study TypeProspective Cohort Study
Study SummaryThe GAPPS study was designed to establish a large biorepository during the pregnancy and early postnatal period that could be used for research on reducing adverse birth outcomes. Pregnant women were eligible if they were older than 18 years of age, English-speaking and had plans to deliver at the hospital in which they enrolled. Eligibility for ECHO-PATHWAYS included the following: recruitment at a Washington study site, consent to contact for future research, at least one pregnancy urine sample available, pregnancy questionnaire data collected and child age between 4–8 years old. GAPPS-PW has two study sites, Seattle, Washington, and Yakima, Washington. GAPPS is conducting two middle childhood visits – one at age 5-6 years and another at 8-9 years. The research is supported by NIH (UG3/UH3OD023271, P30ES007033, UL1 TR002319). This research was conducted using specimens and data collected and stored on behalf of the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS) Repository. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. GAPPS is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375 ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382 North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857 Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539 Citation: LeWinn KZ, Karr CJ, Hazlehurst M, Carroll K, Loftus C, Nguyen R, Barrett E, Swan SH, Szpiro AA, Paquette A, Moore P, Spalt E, Younglove L, Sullivan A, Colburn T, Byington N, Sims Taylor L, Moe S, Wang S, Cordeiro A, Mattias A, Powell J, Johnson T, Norona-Zhou A, Mason A, Bush NR, Sathyanarayana S. Cohort profile: the ECHO prenatal and early childhood pathways to health consortium (ECHO-PATHWAYS). BMJ Open. 2022 Oct 21;12(10):e064288. doi: 10.1136/bmjopen-2022-064288. PMID: 36270755; PMCID: PMC9594508.
Institute
University of Washington
DepartmentEnvironmental and Occupational Health Sciences
Last NameSathyanarayana
First NameSheela
Address1410 NE Campus Parkway Seattle, WAS 98195
Emailsheela.sathyanarayana@seattlechildrens.org
Phone(206) 884-7591
Submit Date2023-06-29
Total Subjects323
Study CommentsHHEAR Project EM20-0011, ECHO Project EC0376
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Chear StudyYes
Analysis Type DetailLC-MS
Release Date2024-07-01
Release Version1
Sheela Sathyanarayana Sheela Sathyanarayana
https://dx.doi.org/10.21228/M8VM7H
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001724
Project DOI:doi: 10.21228/M8VM7H
Project Title:The ECHO Cohort Exposome: First Steps using HHEAR Analysis – An Opportunity for ALL ECHO Cohorts to Contribute Type A Samples – Untargeted Analysis (GAPPS Cohort)
Project Type:C18 Reversed-Phase Broad Spectrum Metabolomics
Project Summary:This project was funded by the NIH Environmental influences on Child Health Outcomes (ECHO) Program. Untargeted metabolomics profiling data was acquired from urine samples provided by 14 ECHO cohorts.
Institute:NC HHEAR Hub
Department:Untargeted Analysis
Laboratory:Sumner Lab
Last Name:Rushing
First Name:Blake
Address:Nutrition Research Institute , University of North Carolina at Chapel Hill, 500 Laureate Way Kannapolis, NC 28081
Email:blake_rushing@unc.edu
Phone:(704) 282-9838
Funding Source:This research was supported by the Environmental influences on Child Health Outcomes (ECHO) program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The GAPPS ECHO Cohort is supported by the National Institutes of Health NIH (UG3/UH3OD023271, P30ES007033) and the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375; ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382; North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857; Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539
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