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MB Sample ID: SA074953
Local Sample ID: | V034 |
Subject ID: | SU001142 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Age Or Age Range: | 30-60 years old |
Weight Or Weight Range: | 52.3-176.6 kg |
Gender: | Male and female |
Human Medications: | To be included in the study all participants had to be taking an atypical (second-generation) antipsychotic |
Human Inclusion Criteria: | DSM IV diagnosis of a schizophrenia spectrum diagnosis who had been taking an atypical antipsychotic for at least 6 months, with no changes in antipsychotic regimen for 8 weeks preceding the baseline visit. Twenty age and sex matched obese and nonobese participants without mental health diagnoses were included to match the BMI range of the patients with schizophrenia as BMI controls. |
Human Exclusion Criteria: | Current use of insulin, diagnosis of diabetes mellitus type 2 prior to antipsychotic exposure, active substance abuse diagnosis |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
Sampleprep ID: | SP001149 |
Sampleprep Summary: | Serum samples were subjected to a 1:1 methanol:choloroform extraction, then dried with a speedvac. Prior to fatty acid analysis, the lipid fractions were resuspended and purified by TLC prior to GC analysis. This is described in more detail in the attached document, with sample prep summaries for the NMR component of this study included as well. |
Sampleprep Protocol ID: | EllingrodSamplePrepProtocol |
Sampleprep Protocol Filename: | EllingrodSamplePrepProtocols.pdf |
Extraction Method: | 1:1 methanol:chloroform |
Sample Resuspension: | hexane |
Sample Spiking: | C17:0 methyl ester |