Summary of Study ST000417
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000326. The data can be accessed directly via it's Project DOI: 10.21228/M8C31Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST000417 |
Study Title | Controlled Human Exposure to Particulate Matter (PM) and Gaseous Co-Pollutants |
Study Type | Exposome Evaluation |
Study Summary | This study is designed to provide the environmental aspects to support both the acquisition of study samples and the advancement of environmental chemical speciation information and data analyis needed. The aims of the study are as follows:1)Do the metabolomics profiles appear to be impacted by exposure to PM and NO2+PM. 2)are the metabolomic profiles related to the PM and NO2+PM distinct 3)which features (chemical or physical) of the PM and NO2+PM have the most significant impact on the metabolomic profiles. |
Institute | RTI International |
Department | RCMRC |
Last Name | Sumner |
First Name | Susan |
Address | 3040 E Cornwallis Road, Research Triangle Park, NC, 27519, USA |
ssumner@rti.org | |
Phone | 919-541-7479 |
Submit Date | 2016-06-15 |
Num Groups | 3 |
Total Subjects | 87 |
Num Males | 47 |
Num Females | 40 |
Raw Data Available | Yes |
Raw Data File Type(s) | cdf |
Analysis Type Detail | GC-MS |
Release Date | 2018-06-05 |
Release Version | 1 |
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Sample Preparation:
Sampleprep ID: | SP000930 |
Sampleprep Summary: | Aliquots of 30µL plasma were mixed with 1mL 3:3:2 ACN:IPA:H2O by vortex mixer then centrifuged. Supernatant recovered. Archived 450µL of supernatant. Continued prep of remaining 450µL supernatant. Evaporated to dryness w/speed vac. Formation of methoximes by adding 10µL of 40mg/mL MeOx in pyridine to each sample. Placed onto Thermomixer for 90 min at 30⁰C. Then FAME retention index markers and MSTFA added to each sample for derivatization step. Samples returned to Thermomixer for 45 min at 70⁰C. |