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MB Sample ID: SA036524
Local Sample ID: | ms5944-15 |
Subject ID: | SU000670 |
Subject Type: | Mouse |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |
Species Group: | Mammal |
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Treatment:
Treatment ID: | TR000684 |
Treatment Summary: | Studies will be performed in 12-16 week old male mdx mice, C57BL10 control mice, and nNOS-/- mice obtained from Jackson Laboratory. All protocols will be approved by the Penn State College of Medicine Institutional Animal Care and Use Committee. Treadmill Exercise: Mice will run on a horizontal treadmill (Columbus Instruments) to assess fatigue by a single bout of exercise beginning at 5 m/min for 5 min followed by 1 m/min increases every minute until exhaustion. Electric shocks will not be used to stimulate running due to adverse effects in mdx mice. |