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MB Sample ID: SA054621
Local Sample ID: | TC7 |
Subject ID: | SU000958 |
Subject Type: | Rat |
Subject Species: | Rattus norvegicus |
Taxonomy ID: | 10116 |
Genotype Strain: | Sprague-dawley |
Age Or Age Range: | 8 weeks |
Weight Or Weight Range: | 300-400 g |
Gender: | male |
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Treatment:
Treatment ID: | TR000972 |
Treatment Summary: | Unilateral contusions of the lateral frontoparietal cortex were created using a controlled cortical impact (CCI) device (Pittsburgh Precision Instruments, Pittsburgh, PA) following published procedures. Rats were anesthetized (induction, 5% isoflurane; maintenance 2-3% isoflurane), mounted in a stereotaxic frame and a 6 mm craniectomy was made over the left frontoparietal cortex (center: -3.0 mm AP, +2.0 mm ML from bregma). A pneumatic piston (tip diameter=5 mm; positioned 15 degrees from vertical in the coronal plane) impacted the cortical tissue to a depth of 2 mm (velocity=4 m/s, duration=200 ms), values consistent with a moderate TBI insult |