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MB Sample ID: SA220331
Local Sample ID: | xeno_L_EA_A_25_1_2 |
Subject ID: | SU002380 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |
Genotype Strain: | CBA nude (N:NIH(S)II-nu/nu) |
Age Or Age Range: | 6 to 7-weeks old |
Gender: | Female |
Animal Animal Supplier: | i3S Animal Facility (Porto, Portugal) |
Animal Housing: | ICBAS-UP Rodent Animal House Facility (Porto, Portugal) |
Animal Light Cycle: | 12h light/dark cycles (7.00 AM lights on) |
Animal Feed: | ad libitum |
Animal Water: | ad libitum |
Animal Inclusion Criteria: | Healthy animails |
Species Group: | CBA nude (N:NIH(S)II-nu/nu) |
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Treatment:
Treatment ID: | TR002392 |
Treatment Summary: | At day 25 post-implantation, 8 animals were randomly chosen into three groups to receive the treatment with either (i) vehicle (phosphate-buffered saline, PBS) - controls, (ii) cDDP (2 mg/kg/day), or (iii) Pd2Spm (5 mg/kg/day), via intraperitoneal injection, during five consecutive days. Two control animals were excluded from the study since they developed ulcerated tumors (at day 28 post-implantation) and needed to be prematurely euthanized. |
Treatment Route: | Intraperitoneal injection |
Treatment Dosevolume: | 500 microliters |
Treatment Vehicle: | PBS (phosphate-buffered saline solution) |