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MB Sample ID: SA220362
| Local Sample ID: | xeno_L_EL_C_29b_1_2 |
| Subject ID: | SU002381 |
| Subject Type: | Mammal |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
| Genotype Strain: | CBA nude (N:NIH(S)II-nu/nu) |
| Age Or Age Range: | 6 to 7-weeks old |
| Gender: | Female |
| Animal Animal Supplier: | i3S Animal Facility (Porto, Portugal) |
| Animal Housing: | ICBAS-UP Rodent Animal House Facility (Porto, Portugal) |
| Animal Light Cycle: | 12h light/dark cycles (7.00 AM lights on) |
| Animal Feed: | ad libitum |
| Animal Water: | ad libitum |
| Animal Inclusion Criteria: | Healthy animails |
| Species Group: | CBA nude (N:NIH(S)II-nu/nu) |
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Treatment:
| Treatment ID: | TR002393 |
| Treatment Summary: | At day 25 post-implantation, 8 animals were randomly chosen into three groups to receive the treatment with either (i) vehicle (phosphate-buffered saline, PBS) - controls, (ii) cDDP (2 mg/kg/day), or (iii) Pd2Spm (5 mg/kg/day), via intraperitoneal injection, during five consecutive days. Two control animals were excluded from the study since they developed ulcerated tumors (at day 28 post-implantation) and needed to be prematurely euthanized. |
| Treatment Route: | Intraperitoneal injection |
| Treatment Dosevolume: | 500 microliters |
| Treatment Vehicle: | PBS (phosphate-buffered saline solution) |
