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MB Sample ID: SA236531
Local Sample ID: | TFA-P9 |
Subject ID: | SU002443 |
Subject Type: | Mammal |
Subject Species: | Rattus norvegicus |
Taxonomy ID: | 10116 |
Age Or Age Range: | 26 weeks of age |
Weight Or Weight Range: | 320-460 grams |
Gender: | Male |
Animal Animal Supplier: | RRRC (University of Missouri) |
Animal Housing: | Center for Comparative Medicine UConn |
Animal Feed: | Modified AIN-93G diet from Research Diets |
Animal Water: | ab libitum |
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Treatment:
Treatment ID: | TR002455 |
Treatment Summary: | Rats were fed two doses of TP-252 equivalent to consuming 1.3 and 2.6 g/kg/day for LD TP-252 and HD TP-252, respectively. Alternatively, rats were also fed a diet containing 2% EPA-FFA in their diet (equivalent to 1.14 g/kg/day of EPA). In groups receiving naproxen, the dose of naproxen was 11.4 mg/kg/day, or roughly 4 mg/rat/day. These treatment groups were carried out for the 20 weeks, and then animals were sacrificed and tissue collected and analyzed. |