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MB Sample ID: SA346777
Local Sample ID: | DS2-039-015 |
Subject ID: | SU003303 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Gender: | Not applicable |
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Treatment:
Treatment ID: | TR003312 |
Treatment Summary: | All animal procedures were carried out in accordance with the IACUC-approved protocol of Cincinnati Children’s Hospital Medical Center. Animals were monitored daily by Veterinary Services. For subcutaneous tumor implantation, 1x10^6 B16F10 cells were mixed with matrigel 1:1 and implanted subcutaneously into NOD-SCID IL2Rgnull or C57BL/6 mice, respectively. CAY10566 was suspended in 0.5% Methyl Cellulose in water with 0.2% Tween 80 at 9 parts per 1 part DMSO stock. CAY10566 was administered at 30mg/kg via oral gavage, twice daily, with a drug holiday during the weekends. |