Summary of Study ST002757
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001718. The data can be accessed directly via it's Project DOI: 10.21228/M8N41J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002757 |
| Study Title | The ECHO Cohort Exposome: First Steps using HHEAR Analysis – An Opportunity for ALL ECHO Cohorts to Contribute Type A Samples – Untargeted Analysis (CIOB Cohort) |
| Study Type | Prospective Cohort Study |
| Study Summary | CIOB is a prospective prenatal cohort study measuring maternal exposures to endocrine disrupting chemicals and place-based, perceptual, and biological markers of chronic psychosocial stressors and their relationships to adverse pregnancy outcomes and neurodevelopment in children. We have recruited nearly 800 pregnant participants from two locations in San Francisco; Zuckerberg San Francisco General Hospital (ZSFG), which serves primarily low income and Latinx patients, and Mission Bay Hospital (MB), which serves higher income and primarily white and Asian patients. We recruited women during their 2nd trimester (13 – 27 weeks) and collected biospecimens (urine, blood, hair, nails) and questionnaires during in-person visits, and umbilical cord and maternal blood and urine at delivery. We measured multiple classes of chemical exposures in our participants including flame retardants, per- and poly-fluoroalkyl substances (PFAS), phthalates, pesticides, phenols, aromatic amines, and we collaborated on development and implementation of shared standardized core data elements, questionnaires at multiple time points during pregnancy and childhood, and collection of biospecimens for chemical and mechanistic analyses during pregnancy and childhood. Please contact Erin DeMicco at erin.demicco@ucsf.edu for questions related to the subject characteristics and outcomes. This research was supported by the Environmental influences on Child Health Outcomes (ECHO) Program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CIOB is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375 ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382 North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857 Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539 |
| Institute | University of California, San Francisco |
| Department | School of Medicine |
| Last Name | Woodruff |
| First Name | Tracey |
| Address | 490 Illinois Street San Francisco CA 94158 |
| Tracey.Woodruff@ucsf.edu | |
| Phone | (415) 476-3198 |
| Submit Date | 2023-06-21 |
| Total Subjects | 463 |
| Study Comments | HHEAR Project EM20-0011, ECHO Project EC0376 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Chear Study | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-06-24 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR002873 |
| Treatment Summary: | N/A |
