Summary of project PR000108

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000108. The data can be accessed directly via it's Project DOI: 10.21228/M8GW2Z This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR000108
Project DOI:doi: 10.21228/M8GW2Z
Project Title:Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model
Project Type:Anesthesia effect study
Project Summary:We examined, for the first time using untargeted and targeted metabolomics, the effect of several commonly-used methods of anesthesia and euthanasia for collection of skeletal muscle, liver, heart, adipose and serum of C57BL/6J mice. The data revealed tissue-specific impacts of different anesthesia and euthanasia strategies. Based on these findings, we present a more optimal collection strategy mammalian tissues and recommend that rodent tissues intended for metabolomics studies be collected under anesthesia rather than post-euthanasia.
Institute:University of Michigan
Department:Internal Medicine
Laboratory:Evans lab / Burant lab
Last Name:Evans
First Name:Charles
Address:6321 Brehm Tower, 1000 Wall St.
Email:chevans@umich.edu
Phone:734-232-8177
Funding Source:National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health

Summary of all studies in project PR000108

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST000121 Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model Mus musculus University of Michigan MS 2015-02-01 1 245 Uploaded data (561.5K)
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