Summary of project PR000119
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000119. The data can be accessed directly via it's Project DOI: 10.21228/M86C76 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000119 |
| Project DOI: | doi: 10.21228/M86C76 |
| Project Title: | Monitoring In Vitro Response of Selenium-Treated Prostate Cells by 1H NMR Spectroscopy |
| Project Type: | Metabolomics by 1H NMR |
| Project Summary: | 1H NMR data of prostate cells treated with selenium showed a decreasing trend in metabolite levels with the largest change exhibited by creatine mainly due to disrupted energy metabolism, and probably due to loss of structural integrity combined with external dissipation of metabolites. Lactate, choline-containing compounds, and glycine levels increased depending on the type of selenium used and the cell type. Principal component analysis (PCA) showed that SeM-treated cells can be distinguished from SeMSC-treated cells, and DU145 PCa from PNT1A normal cells. |
| Institute: | Purdue University |
| Department: | Biology/Chemistry |
| Laboratory: | Biology/Chemistry Dept |
| Last Name: | Isaac-Lam |
| First Name: | Meden |
| Address: | 1401 S US Hwy 421 Westville, Indiana USA |
| Email: | isaaclam@pnc.edu |
| Phone: | 1-219-785-5776 |
| Funding Source: | Indiana Academy of Science |
Summary of all studies in project PR000119
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST000134 | Monitoring In Vitro Response of Selenium-Treated Prostate Cells by 1H NMR Spectroscopy | Homo sapiens | Purdue University | NMR | 2015-01-13 | 1 | 4 | Uploaded data (4.5M) |
