Summary of project PR000209
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000209. The data can be accessed directly via it's Project DOI: 10.21228/M8CP4Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000209 |
| Project DOI: | doi: 10.21228/M8CP4Q |
| Project Title: | Metabolite changes associated with weight loss |
| Project Type: | Feeding study |
| Project Summary: | This study aims to identify changes in metabolites that occur in metabolic tissues, including liver, adipose (epididymal), hypothalamus, and muscle, as well as plsma, in the obese state that are long-lasting and not reversed by weight loss. Mice were divided into three groups termed LFD (low fat diet), HFD (high fat diet), and SW (switch diet from HFD to LFD)(n = 6 per group). All mice were fed normal chow until 12 weeks of age. The LFD group were fed a low fat diet (10% fat) ad libitum for 18 weeks. The HFD diet group were fed high fat diet (60% fat) ad libitum for 18 weeks. The SW group were fed high fat diet for 9 weeks, then low fat diet for 9 weeks after which their body weights returned to similar levels as the LFD group. Each group was analyzed for metabolite and gene expression changes. |
| Institute: | University of California, San Diego |
| Department: | Department of Medicine |
| Laboratory: | Osborn |
| Last Name: | Osborn |
| First Name: | Olivia |
| Address: | 9500 Gilman Dr., La Jolla, CA 92093 |
| Email: | oosborn@ucsd.edu |
| Phone: | +1-858-822-6645 |
| Funding Source: | National Institute of Health U24 DK092993 |
Summary of all studies in project PR000209
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST000257 | NIH WCMC Pilot & Feasibility Project: “Metabolite changes associated with weight loss” | Mus musculus | University of California, Davis | MS | 2015-09-24 | 1 | 90 | Uploaded data (122.5M)* |
