Summary of project PR000421
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000421. The data can be accessed directly via it's Project DOI: 10.21228/M8N316 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000421 |
| Project DOI: | doi: 10.21228/M8N316 |
| Project Title: | Exploratory research on first and second trimester urinary metabolic profiles and fetal growth restriction |
| Project Summary: | From 2010 to 2012, women were recruited into The Infant Development and the Environment Study (TIDES) from obstetrical clinics affiliated with academic medical centers in four U.S. cities. Using previously collected first and second trimester urine samples from this prospective cohort of nearly 800 pregnancies, we designed a nested case control study aimed to determine whether maternal metabolic abnormalities/differences are associated with FGR. To find the patients with fetal growth restriction (FGR), we reviewed de-identified questionnaires and de-identified previously collected data, and performed a growth potential formula considering gestational age, infant gender, maternal and paternal height, and interaction of gestational age with maternal weight. Using a case:control ratio of 1:2, matched on study site, maternal age (± 2 years), parity, and infant's sex, 53 cases were matched to 106 controls for a total of 159 patients, and 318 samples (one in each ttrimester). The samples were analyses by NMR spectroscopy, using Bruker IVDr platform. |
| Institute: | Mayo Clinic |
| Last Name: | Vuckovic |
| First Name: | Ivan |
| Address: | 200 First St. SW, Rochester, Minnesota, 55905, USA |
| Email: | vuckovic.ivan@mayo.edu |
| Phone: | 507-288-0486 |
Summary of all studies in project PR000421
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST000573 | Exploratory research on first and second trimester urinary metabolic profiles and fetal growth restriction | Homo sapiens | Mayo Clinic | NMR | 2018-04-10 | 1 | 322 | Not available |
