Summary of project PR000602
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000602. The data can be accessed directly via it's Project DOI: 10.21228/M8VH5Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000602 |
| Project DOI: | doi: 10.21228/M8VH5Q |
| Project Title: | Biomarkers discovery for Hepatocellular Carcinoma (HCC) |
| Project Summary: | Hepatocellular Carcinoma (HCC) is the most common type of liver cancer. Current diagnosis of HCC relies on the measurement of the level of the serum biomarker, α-fetoprotein (AFP). However, the sensitivity and specificity of AFP are not sufficient for diagnosis of HCC as elevated AFP levels may be seen in patients with cirrhosis or chronic hepatitis too. Therefore, reliable serological biomarkers for early detection of HCC in high-risk population of cirrhotic patients are yet to be found and validated. Metabolomics provides simultaneous assessment of a broad range of metabolites that can potentially serve as indicators of the overall physiology status as well as the response to host and environmental stimuli. It has been broadly used for biomarker discovery and characterization of complex diseases such as cancer. |
| Institute: | Georgetown University |
| Department: | Oncology |
| Laboratory: | Ressom Lab (PI: Habtom W. Ressom, email address hwr@georgetown.edu) |
| Last Name: | Di Poto |
| First Name: | Cristina |
| Address: | 3970 Reservoir Rd., NW, Research Bldg, Room W325, Washington, DC, 20007, USA |
| Email: | cd329@georgetown.edu |
| Phone: | 2026872926 |
Summary of all studies in project PR000602
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST000865 | Identification of Race-Associated Metabolite Biomarkers for Hepatocellular Carcinoma | Homo sapiens | Georgetown University | MS | 2018-03-02 | 1 | 140 | Uploaded data (1.1G)* |
