Summary of project PR000772

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000772. The data can be accessed directly via it's Project DOI: 10.21228/M8WH51 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR000772
Project DOI:doi: 10.21228/M8WH51
Project Title:Role of erythrocyte ADORA2B in Chronic Kidney Disease (CKD)
Project Summary:we have provided both mouse and human evidence that ADORA2B-AMPK signaling cascade-induced 2,3-BPG production is a beneficial erythrocyte response to promote O2 delivery to counteract kidney hypoxia and progression of CKD. These findings pave a way to novel therapeutic avenues in CKD.
Institute:University of Texas Health Science Center at Houston
Department:McGovern Medical School
Last Name:Xia
First Name:Yang
Address:6431 Fannin, MSB 6.202,Houston, TX 77030
Email:yang.xia@uth.tmc.edu
Phone:713-500-5039

Summary of all studies in project PR000772

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
Release
Date
VersionSamplesDownload
(* : Contains raw data)
ST001153 Erythrocyte adenosine A2B receptor-mediated AMPK activation: Counteracting CKD by promoting oxygen delivery Mus musculus University of Texas Health Science Center at Houston MS 2019-07-17 1 11 Uploaded data (127.5K)*
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