Summary of project PR000772
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000772. The data can be accessed directly via it's Project DOI: 10.21228/M8WH51 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Project ID: | PR000772 |
Project DOI: | doi: 10.21228/M8WH51 |
Project Title: | Role of erythrocyte ADORA2B in Chronic Kidney Disease (CKD) |
Project Summary: | we have provided both mouse and human evidence that ADORA2B-AMPK signaling cascade-induced 2,3-BPG production is a beneficial erythrocyte response to promote O2 delivery to counteract kidney hypoxia and progression of CKD. These findings pave a way to novel therapeutic avenues in CKD. |
Institute: | University of Texas Health Science Center at Houston |
Department: | McGovern Medical School |
Last Name: | Xia |
First Name: | Yang |
Address: | 6431 Fannin, MSB 6.202,Houston, TX 77030 |
Email: | yang.xia@uth.tmc.edu |
Phone: | 713-500-5039 |
Summary of all studies in project PR000772
Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
---|---|---|---|---|---|---|---|---|
ST001153 | Erythrocyte adenosine A2B receptor-mediated AMPK activation: Counteracting CKD by promoting oxygen delivery | Mus musculus | University of Texas Health Science Center at Houston | MS | 2019-07-17 | 1 | 11 | Uploaded data (127.5K)* |