Summary of project PR000783
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000783. The data can be accessed directly via it's Project DOI: 10.21228/M8G970 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000783 |
| Project DOI: | doi: 10.21228/M8G970 |
| Project Title: | Metabolomics of World Trade Center Exposed New York City Firefighters |
| Project Type: | C18 Reversed-Phase Broad Spectrum Metabolomics |
| Project Summary: | Particulate matter (PM) exposure and metabolic syndrome (MetSyn) coexist in both industrialized and developing nations. PM and MetSyn are strong risk factors for chronic obstructive pulmonary disease (COPD) and asthma. After the World Trade Center collapse in 9/11/2001, PM-exposed individuals from the Fire Department of New York City (FDNY) developed a progressively lung disease. This nested case-cohort study is composed of never smoking, WTC exposed firefighters with normal pre-9/11 lung function presenting for subspecialty pulmonary evaluation (SPE) before March 2008. Representative cohort controls with serum drawn within six months of 9/11 (n=100). FEV1 at subspecialty exam defined cases: susceptible World Trade Center Lung Injury (WTC-LI) cases (n=50) had FEV1< lower limit of normal (LLN) and resistant WTC-LI cases with FEV1 ≥107% predicted (n=50). This study will determine the metabolomics profile that differentiates firefighters with WTC-LI, firefighters resistant to WTC-LI, and similarly exposed cohort controls. |
| Institute: | University of North Carolina |
| Department: | Nutrition Research Institute |
| Last Name: | Sumner |
| First Name: | Susan |
| Address: | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
| Email: | susan_sumner @unc.edu |
| Phone: | 704-250-5066 |
Summary of all studies in project PR000783
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001171 | Metabolomics of World Trade Center Exposed New York City Firefighters | Homo sapiens | New York University | MS* | 2021-02-26 | 1 | 248 | Uploaded data (21.6G)* |
