Summary of project PR000896
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000896. The data can be accessed directly via it's Project DOI: 10.21228/M8VX0Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000896 |
| Project DOI: | doi: 10.21228/M8VX0Z |
| Project Title: | Pre-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Study |
| Project Type: | Quantitative NMR Metabolomics |
| Project Summary: | To utilize existing serum samples from the phase II clinical trial of L-carnitine treatment for severe sepsis to metabolically phenotype L-carnitine responders and non-responders. Methods: Serum samples collected prior to (T0) and after completion of the infusion (T24, T48) from patients randomized to either low (6 g), intermediate (12g), high (18g) L-carnitine or placebo for the treatment of vasopressor dependent septic shock were assayed by untargeted 1H-nuclear magnetic resonance metabolomics. |
| Institute: | University of Michigan |
| Laboratory: | Stringer NMR Metabolomics Laboratory |
| Last Name: | McHugh |
| First Name: | Cora |
| Address: | 428 Church St, Ann Arbor, MI, 48103, USA |
| Email: | NMRmetabolomics@umich.edu |
| Phone: | 7343530164 |
| Funding Source: | GM111400 |
| Contributors: | Kathleen Stringer, Mike Puskarich, Alan Jones |
Summary of all studies in project PR000896
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001319 | Pre-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Patients | Homo sapiens | University of Michigan | NMR | 2020-09-10 | 1 | 236 | Uploaded data (41.2M)* |
