Summary of project PR000978
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000978. The data can be accessed directly via it's Project DOI: 10.21228/M88Q44 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000978 |
| Project DOI: | doi: 10.21228/M88Q44 |
| Project Title: | Influence of growth medium on the volatilomes of Pseudomonas spp. and Staphylococcus spp. |
| Project Type: | Untargeted MS |
| Project Summary: | Pseudomonas aeruginosa and Staphylococcus aureus are the predominant opportunistic lung pathogens persons with CF [2017 CF Foundation Annual Report] and are leading causes of respiratory failure and mortality [Malhotra, et al. Clin Microbiol Rev, 2019]. Currently, sputum culture remains the standard of care for lung infection detection, but sputum production is on the decline due to improvements in CF therapies. To fill this diagnostic gap, we are working toward the development of breath tests for lung infections by characterizing the volatile metabolome (or “volatilome”) of P. aeruginosa and S. aureus. In this study, we explored the influence of growth medium on the volatilomes of two strains of P. aeruginosa (PAO1 and PA14) and S. aureus, as well as two other species from the same genera, S. epidermidis and P. chlororaphis. We hypothesized that the volatilomes would be influenced by the growth medium, but that biological differences between these species and strains would dominate the volatilomes and facilitate identification. |
| Institute: | Arizona State University |
| Department: | School of Life Sciences |
| Laboratory: | Heather D. Bean Lab |
| Last Name: | Bean, Ph.D. |
| First Name: | Heather |
| Address: | PO Box 874501 Tempe, AZ 85287 |
| Email: | heather.d.bean@asu.edu |
| Phone: | 480-727-3395 |
| Publications: | Jenkins, C. L., H. D. Bean (2020). Influence of media on the differentiation of Staphylococcus spp. by volatile compounds. Journal of breath research 14, 016007 doi:10.1088/1752-7163/ab3e9d |
Summary of all studies in project PR000978
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001426 | Dependence of the Staphylococcal Volatilome Composition on Microbial Nutrition | Staphylococcus epidermidis | Arizona State University | MS* | 2020-07-30 | 1 | 77 | Uploaded data (7.3G)* |
