Summary of project PR001022
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001022. The data can be accessed directly via it's Project DOI: 10.21228/M8KT26 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001022 |
| Project DOI: | doi: 10.21228/M8KT26 |
| Project Title: | Effects of glucagon infusion on plasma metabolome in individuals with overweight/obesity |
| Project Summary: | Objective: We sought to identify the circulating metabolites that would serve as markers of glucagon action. Design: In this study, we performed a continuous 72-hour glucagon infusion in healthy individuals with overweight/obesity. Participants were randomized to either glucagon (12.5 ng/kg/min) (GCG 12.5) or glucagon (25 ng/kg/min) GCG 25 or a placebo control were included. A comprehensive metabolomics analysis was then performed from plasma isolated at several time points during the infusion to identify markers of glucagon activity. |
| Institute: | Translational Research Institute- AdventHealth Orlando |
| Last Name: | Whytock |
| First Name: | Katie |
| Address: | 301 E Princeton St, FL, USA, 32804 |
| Email: | Katie.Whytock@adventhealth.com |
| Phone: | 3219459982 |
| Funding Source: | Sanofi |
Summary of all studies in project PR001022
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001515 | A Metabolomic Signature of Glucagon Action in Healthy Individuals with Overweight/Obesity Humans | Homo sapiens | Translational Research Institute- AdventHealth Orlando | MS | 2020-12-01 | 1 | 187 | Not available |
