Summary of project PR001050

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001050. The data can be accessed directly via it's Project DOI: 10.21228/M8ZX18 This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001050
Project DOI:doi: 10.21228/M8ZX18
Project Title:Parallel multi-omics in high-risk subjects for the identification of integrated biomarker signatures of 4 type 1 diabetes
Project Summary:Biomarkers are of paramount importance for early disease detection and are particularly valuable in type 1 diabetes (T1D) to prevent significant β cell loss before the onset of clinical symptoms. Thus far, single-omics studies have failed to identify such T1D biomarkers. Here, we present proof-of-concept studies to demonstrate the potential for identifying integrated biomarker signature(s) of T1D using parallel multi-omics. Blood from human subjects at high risk for T1D (and healthy controls; n=4 each) were subjected to parallel unlabeled proteomics, metabolomics, lipidomics, and transcriptomics. The integrated dataset was analyzed using Ingenuity Pathway Analysis (IPA) software for disturbances in the at-risk subjects compared to the controls.
Institute:University of Miami
Last Name:Bhattacharya
First Name:Sanjoy
Address:1638 NW 10th Avenue, Room 706-A, Miami, FL 33136

Summary of all studies in project PR001050

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST001642 Lipidomics in high-risk subjects for the identification of integrated biomarker signatures of type 1 diabetes Homo sapiens University of Miami MS 2021-01-25 1 9 Uploaded data (1.9G)*