Summary of project PR001122
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001122. The data can be accessed directly via it's Project DOI: 10.21228/M8P686 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001122 |
| Project DOI: | doi: 10.21228/M8P686 |
| Project Title: | Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations |
| Project Summary: | Poor metabolic health, characterized by insulin resistance and dyslipidemia, is higher in people living with HIV (PLWH) and has been linked with inflammation, anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). Metabolic disease is associated with gut microbiome composition outside the context of HIV but has not been deeply explored in HIV infection nor in high-risk men who have sex with men (HR-MSM), who have a highly altered gut microbiome composition. Furthermore, the contribution of increased bacterial translocation and associated systemic inflammation that has been described in HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic approach to explore relationships between gut microbes, immune phenotypes, diet, and metabolic health across ART-treated PLWH with and without LD; untreated PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the plasma metabolome. |
| Institute: | University of Colorado Anschutz Medical Campus |
| Last Name: | Reisdorph |
| First Name: | Nichole |
| Address: | 12850 East Montview Blvd, Aurora, CO, 80045, USA |
| Email: | nichole.reisdorph@cuanschutz.edu |
| Phone: | 303-724-9234 |
Summary of all studies in project PR001122
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001750 | Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations | Homo sapiens | University of Colorado Anschutz Medical Campus | MS* | 2021-05-04 | 1 | 54 | Uploaded data (9.3G)* |
