Summary of project PR001155
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001155. The data can be accessed directly via it's Project DOI: 10.21228/M8DH5P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001155 |
| Project DOI: | doi: 10.21228/M8DH5P |
| Project Title: | Nested case–control study of environmental exposure within the ongoing Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) pregnancy cohort. |
| Project Summary: | Preterm birth is the leading cause of infant mortality worldwide, and also greatly increases the risk of developing serious health complications in childhood and throughout life. Conditions that contribute to preterm birth remain largely unclear, though an influence by environmental exposures is suspected but poorly understood. In our preliminary work, we found that exposure to common chemicals, such as phthalates and bisphenol A (BPA), may contribute to this serious but understudied public health problem. We also observed strong associations between phthalates/BPA and general markers of oxidative stress, and in turn between these general markers of oxidative stress and risk of preterm birth. In this nested case-control study within an ongoing cohort of pregnant women in Puerto Rico (PROTECT), we will explore untargeted lipidomics, as well as levels of eicosanoids specific to arachidonic acid oxidation pathways, in relation to both environmental exposures and preterm birth. |
| Institute: | University of Michigan |
| Department: | Nutritional Sciences |
| Laboratory: | Meeker Lab |
| Last Name: | Meeker |
| First Name: | John |
| Address: | Ann Arbor, MI |
| Email: | meekerj@umich.edu |
| Phone: | 734-764-7184 |
Summary of all studies in project PR001155
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001828 | Nested case–control study of environmental exposure within the ongoing Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) pregnancy cohort. | Homo sapiens | University of Michigan | MS* | 2021-12-15 | 1 | 100 | Uploaded data (36.3G)* |
| ST001831 | Nested case–control study of environmental exposure within the ongoing Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) pregnancy cohort (part II) | Homo sapiens | University of Michigan | MS | 2021-12-15 | 1 | 100 | Uploaded data (2.2G)* |
