Summary of project PR001165

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001165. The data can be accessed directly via it's Project DOI: 10.21228/M8411V This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR001165
Project DOI:doi: 10.21228/M8411V
Project Title:Untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer’s Disease
Project Type:Untargeted Metabolomics analysis
Project Summary:Recent research regarding amino acid metabolism has shown that there may be a link between obesity and Alzheimer’s Disease (AD). This work reports a metabolomics study using untargeted mass spectrometry-based metabolomic strategies to investigate the metabolic changes that occur in AD and obesity. APPSwe/PS1ΔE9 (APP/PSEN1) transgenic mice (to represent familial or early-onset AD) and wild-type litter mater controls were fed either a high-fat diet (HFD, 60% kcal from lard), low-fat diet (LFD, 10% kcal from lard) from 2 months of age, or reversal diet (REV, high-fat followed by low-fat from 9.5 months).
Institute:Vanderbilt University
Department:Chemistry
Laboratory:Center for Innovative Technology
Last Name:Codreanu
First Name:Simona
Address:3009, Liberty Hills Drive
Email:SIMONA.CODREANU@VANDERBILT.EDU
Phone:6153477458

Summary of all studies in project PR001165

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST001848 Untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer’s Disease Mus musculus Vanderbilt University MS* 2021-08-31 1 36 Uploaded data (13.4G)*
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