Summary of project PR001255
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001255. The data can be accessed directly via it's Project DOI: 10.21228/M8GT41 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001255 |
| Project DOI: | doi: 10.21228/M8GT41 |
| Project Title: | Gene-therapy enhances CSF’s anti-oxidative activity to mitigate chemotherapy side effects |
| Project Type: | Anti-oxidative Metabolism Measurement in CSF of MTX-treated mice under gene therapy by quantitative LC/MS method |
| Project Summary: | In order to test the protective activity of SOD3 levels on the redox state of the CSF of MTX-treated mice, targeted metabolomics on CSF was employed at different timepoints after treatment, on mice of both sexes, at various levels of impacted hSOD3 expression. |
| Institute: | Boston Children's Hospital |
| Department: | Pathology |
| Laboratory: | Naama Kanarek |
| Last Name: | Petrova |
| First Name: | Boryana |
| Address: | 300 Longwood Av, Boston, MA, 2115, USA |
| Email: | boryana.petrova@childrens.harvard.edu |
| Phone: | 6173557433 |
Summary of all studies in project PR001255
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001974 | Anti-oxidative metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (I) | Mus musculus | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 40 | Uploaded data (4.8G) |
| ST001975 | Anti-oxidative metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (II) | Mus musculus | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 48 | Uploaded data (5.5G)* |
| ST001976 | Anti-oxidation metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (III) | Mus musculus | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 40 | Uploaded data (4.6G) |
| ST001977 | Anti-oxidative metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (IV) | Homo sapiens | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 37 | Uploaded data (1.6G) |
| ST001978 | Anti-oxidation metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (V) | Homo sapiens | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 80 | Uploaded data (7.7G)* |
| ST001979 | Anti-oxidation metabolism measurement in mammalian cells and tissues by quantitative LC/MS method (VI) | Mus musculus | Boston Children's Hospital, Harvard Medical School | MS | 2022-08-29 | 1 | 49 | Uploaded data (5.4G) |