Summary of project PR001325
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001325. The data can be accessed directly via it's Project DOI: 10.21228/M8FM6D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001325 |
| Project DOI: | doi: 10.21228/M8FM6D |
| Project Title: | Serum NMR profiling reveals differential alterations in the lipoproteome induced by Pfizer-BioNTech vaccine in COVID-19–recovered subjects and naïve subjects |
| Project Type: | NMR-based metabolomic analysis |
| Project Summary: | 1H NMR spectra of sera have been used to define the changes induced by vaccination with Pfizer-BioNTech vaccine (2 shots, 21 days apart) in 10 COVID-19-recovered subjects and 10 COVID-19-naïve subjects at different time points, starting from before vaccination, then weekly until 7 days after second injection, and finally 1 month after the second dose. The data show that vaccination does not induce any significant variation in the metabolome, whereas it causes changes at the level of lipoproteins. The effects are different in the COVID-19-recovered subjects with respect to the naïve subjects, suggesting that a previous infection reduces the vaccine modulation of the lipoproteome composition. |
| Institute: | University of Florence |
| Department: | Department of chemistry |
| Laboratory: | Metabolomics |
| Last Name: | Ghini |
| First Name: | Veronica |
| Address: | via Luigi Sacconi 6 |
| Email: | ghini@cerm.unifi.it |
| Phone: | +390554574266 |
Summary of all studies in project PR001325
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002086 | Serum NMR profiling reveals differential alterations in the lipoproteome induced by Pfizer-BioNTech vaccine in COVID-19–recovered subjects and naïve subjects | Homo sapiens | University of Florence | NMR* | 2022-02-28 | 1 | 116 | Uploaded data (305.1M)* |
