Summary of project PR001326
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001326. The data can be accessed directly via it's Project DOI: 10.21228/M89T2Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001326 |
| Project DOI: | doi: 10.21228/M89T2Q |
| Project Title: | Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients |
| Project Type: | NMR-based metabolomics |
| Project Summary: | 1H NMR spectra of EDTA-plasma from 246 COVID-19-positive subjects in the acute phase of infection were compared to those of 95 COVID-19-recovered subjects. The two cohorts are largely different (discrimination accuracy > 93%) due to a pool of 16 metabolites and 74 lipoprotein parameters significantly up- or down-regulated in the patients and within the healthy range in the recovered subjects. In 28 post-acute COVID-19-positive patients, the metabolites levels are reverted back to normality whereas the lipoprotein parameters are still altered. Therefore, the metabolite biomarkers might be used as the timeliest sign of the individual response to treatment or spontaneous healing. |
| Institute: | University of Florence |
| Department: | Department of Chemistry |
| Laboratory: | Metabolomics |
| Last Name: | Ghini |
| First Name: | Veronica |
| Address: | via Luigi Sacconi 6 |
| Email: | ghini@cerm.unifi.it |
| Phone: | +390554574266 |
| Funding Source: | COMETA project, funded by the Tuscany Region,Italy |
Summary of all studies in project PR001326
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002087 | Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients | Homo sapiens | University of Florence | NMR | 2022-03-16 | 1 | 368 | Uploaded data (5.8M)* |
| ST002404 | Profiling Metabolites and Lipoproteins in COMETA, an Italian Cohort of COVID-19 patients-part 2 | Homo sapiens | University of Florence | NMR | 2023-11-09 | 1 | 605 | Uploaded data (3.8M)* |
