Summary of project PR001343
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001343. The data can be accessed directly via it's Project DOI: 10.21228/M8439K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001343 |
| Project DOI: | doi: 10.21228/M8439K |
| Project Title: | Exposures to Metals in Pregnant Women and the Impact on Fetal Development and Birth Outcomes in Suriname |
| Project Type: | C18 Reversed-Phase Broad Spectrum Metabolomics |
| Project Summary: | The Caribbean Consortium for Environmental and Occupational Health, a NIH-funded integrated research and research training program, started in 2015. The research component is a population-based prospective longitudinal environmental epidemiologic cohort study addressing the potential adverse impact of chemical and non-chemical environmental exposures in mother/child dyads in Suriname. The study determines associations between exposures to neurotoxicants (metals and pesticides) and essential elements and non-chemical stressors in pregnant women and the impact on birth and neurodevelopmental outcomes. The study population consists of culturally diverse pregnant women (n=1143; ages: 16-49 years) and their babies/children (n=1069). Data collection takes place twice prenatally, at birth, 12, 36, and 48 months. Through HHEAR, targeted and untargeted (metabolomics) analyses will characterize exposure to metals in a sub-cohort of pregnant women for whom exposure data are not yet available. This expanded exposure analysis will enable a more comprehensive cumulative risk assessment of adverse birth and neurodevelopmental outcomes in the overall cohort. |
| Institute: | NC HHEAR Hub |
| Department: | Untargeted Analysis |
| Laboratory: | Sumner Lab |
| Last Name: | Li |
| First Name: | Yuan |
| Address: | Nutrition Research Institute, UNC-CH,500 Laureate Way, Kannapolis, NC 28081 |
| Email: | yuanyli4@unc.edu |
| Phone: | 984-377-0693 |
| Funding Source: | The Caribbean Consortium for Environmental and Occupational Health is funded by the Fogarty International Center of the National Institutes of Health (U01TW010087, U2RTW010104). Untargeted metabolomics analyses were conducted at the North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X (U2C ES030857), and support provided by the Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc.: O’Brien B (U24 ES026539), and the Human Health Exposure Analysis Data Center: Icahn School of Medicine at Mount Sinai: Teitelbaum S (U2CES026555) |
Summary of all studies in project PR001343
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002118 | Exposures to Metals in Pregnant Women and the Impact on Fetal Development and Birth Outcomes in Suriname | Homo sapiens | University of Pittsburgh | MS* | 2023-03-22 | 1 | 824 | Uploaded data (81.2G)* |
