Summary of project PR001405

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001405. The data can be accessed directly via it's Project DOI: 10.21228/M83T37 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR001405
Project DOI:doi: 10.21228/M83T37
Project Title:Metabolic profiling of induced acute pancreatitis and pancreatic cancer progression in a mutant Kras mouse model
Project Type:NMR-based metabolomics
Project Summary:Untargeted Nuclear Magnetic Resonance (NMR) metabolomics of polar extracts from the pancreata of a caerulin-induced mouse model of pancreatitis (Pt) and of a transgenic mouse model of pancreatic cancer (PCa) were used to find metabolic markers of Pt and to characterize the metabolic changes accompanying PCa progression. Using multivariate analysis a 10-metabolite metabolic signature specific to Pt tissue was found to distinguish the benign condition from both normal tissue and precancerous tissue (low grade pancreatic intraepithelial neoplasia, PanIN, lesions).
Institute:University of Aveiro
Department:Department of Chemistry and CICECO-Aveiro Institute of Materials
Laboratory:Metabolomics from Ana M. Gil
Last Name:Carneiro
First Name:Tatiana J.
Address:Campus Universitário de Santiago, Aveiro, Aveiro, 3810-193, Portugal
Email:tatiana.joao@ua.pt
Phone:+351 234 370 200

Summary of all studies in project PR001405

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST002202 Metabolic profiling of induced acute pancreatitis and pancreatic cancer progression in a mutant Kras mouse model Mus musculus University of Aveiro NMR* 2022-09-14 1 40 Uploaded data (37M)*
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