Summary of project PR001608
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001608. The data can be accessed directly via it's Project DOI: 10.21228/M8VB03 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001608 |
| Project DOI: | doi: 10.21228/M8VB03 |
| Project Title: | Tryptophan metabolites that circulate at significant levels in vivo are not subject to an autoregulatory feedback loop between the AHR and CYP1A1. |
| Project Type: | MS quantitative study |
| Project Summary: | We establish that six tryptophan metabolites are essentially not CYP1A1 substrates and the level of these metabolite in mouse serum are not affected by a lack of CYP1A1 or any other Aryl hydrocarbon Receptor (AHR) dependent metabolic pathway expression in vivo. These results establish that tryptophan metabolites that circulate at significant levels in vivo are not subject to an autoregulatory feedback loop between the AHR and CYP1A1. |
| Institute: | The Pennsylvania State University |
| Last Name: | Dong |
| First Name: | Fancong |
| Address: | 309 Life Sciences Building, State college, PA, 16802, USA |
| Email: | fxd93@psu.edu |
| Phone: | 8148651415 |
Summary of all studies in project PR001608
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002491 | Six tryptophan metabolites in mouse serum | Mus musculus | Pennsylvania State University | MS | 2023-04-03 | 1 | 56 | Uploaded data (1.1G)* |
