Summary of project PR001667
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001667. The data can be accessed directly via it's Project DOI: 10.21228/M87727 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001667 |
| Project DOI: | doi: 10.21228/M87727 |
| Project Title: | Per- and poly-fluoroalkyl substances (PFAS) Exposures and Child Health (PEACH) Study: Using targeted exposure assessment and untargeted metabolic profiling to characterize molecular pathways and mechanisms underlying PFAS toxicity on adverse birth and child health outcomes |
| Project Type: | C18 Reversed-Phase Broad Spectrum Metabolomics |
| Project Summary: | The overarching goal of the Per- and poly-fluoroalkyl substances Exposures And Child Health (PEACH) Study is to apply an advanced untargeted metabolomics workflow to investigate associations between PFAS levels, perturbations in maternal and newborn metabolome and adverse birth outcomes. The Emory ECHO team has established a socio-economically diverse, exceptionally phenotyped African American (AA) maternal-child cohort that enrolls pregnant women in the early prenatal period and extends dyad follow-up through age five. PEACH draws from repeated metabolic profiling on a subset of 320 AA pregnant people within the Atlanta ECHO cohort, PFAS assessment, and untargeted metabolomics from newborn blood spots (n=279). Please contact Drs. Donghai Liang (Donghai.liang@emory.edu) and Anne Dunlop (amlang@emory.edu) via email for questions related to the subject characteristics and outcomes. |
| Institute: | NC HHEAR Hub |
| Department: | Untargeted Analysis |
| Laboratory: | Sumner Lab |
| Last Name: | Rushing |
| First Name: | Blake |
| Address: | Nutrition Research Institute, UNC-CH, 500 Laureate Way, Kannapolis, NC 28081 |
| Email: | blake_rushing@unc.edu |
| Phone: | (704) 282-9838 |
| Funding Source: | This research was supported by the Environmental influences on Child Health Outcomes (ECHO) OIF program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. PEACH is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375; ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382; North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857; Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539 |
Summary of all studies in project PR001667
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002692 | Per- and poly-fluoroalkyl substances (PFAS) Exposures and Child Health (PEACH) Study: Using targeted exposure assessment and untargeted metabolic profiling to characterize molecular pathways and mechanisms underlying PFAS toxicity on adverse birth and child health outcomes | Homo sapiens | Emory University | MS* | 2024-04-26 | 1 | 363 | Uploaded data (38.1G)* |
