Summary of project PR001687

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001687. The data can be accessed directly via it's Project DOI: 10.21228/M8NB07 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR001687
Project DOI:doi: 10.21228/M8NB07
Project Title:Repeated Exposure to Wood Smoke Alters Pulmonary Gene and Metabolic Profiles
Project Summary:This project aims to evaluate the association of eucalyptus wood smoke exposure with perturbations to lung metabolism in a pre-clinical rat model. This cross-sectional study of male Long-Evans rats were exposed whole body to eucalyptus smoke for 4 consecutive days on week 1, followed by a 3-day break, and 3 subsequent days of smoke exposure on week 2. The smoke exposures were set to a target CO of 10ppm for the low smoke group and 20ppm for the high smoke group. Animal were sacrificed and lungs were extracted for metabolomics analysis. Exposures to eucalyptus smoke and biological perturbations to lung metabolism will be associated with known metabolic dysregulation associated with smoke exposures.
Institute:Emory University
Department:School of Medicine
Laboratory:Clinical Biomarkers Laboratory
Last Name:Tran
First Name:ViLinh
Address:615 Michael St, Suite 225, Atlanta, GA 30322, USA
Email:vtran6@emory.edu
Phone:404-727-5091
Contributors:Matthew R. Smith, PdD, Collette M. Miller, PhD, Kymberly M. Gowdy, PhD, Dean P. Jones, PhD

Summary of all studies in project PR001687

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST002721 Repeated Exposure to Wood Smoke Alters Pulmonary Gene and Metabolic Profiles Rattus norvegicus Emory University MS* 2024-05-13 1 32 Uploaded data (11.4G)*
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