Summary of project PR001810
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001810. The data can be accessed directly via it's Project DOI: 10.21228/M8RD98 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Project ID: | PR001810 |
Project DOI: | doi: 10.21228/M8RD98 |
Project Title: | Identifying the impact of RelA overexpression in triple negative breast cancer cells using mass spectroscopy-based metabolomics analysis |
Project Type: | LC-MS/MS |
Project Summary: | In this research study, metabolomics alterations associated with the overexpression of RelA in the TNBC cell line, MDA-MB-231, were investigated using liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) technique. UHPLC-QTOF-MS is a rapid, sensitive, high-resolution mass spectrometry technology that detects and identifies fragment patterns of compounds in complex samples. This analysis would unravel the key metabolites modified due to RelA overexpression, thus highlighting the altered signaling pathways behind the aggressiveness and chemoresistance of TNBC through NF-?B alteration. |
Institute: | Sharjah Institute for Medical Research |
Last Name: | Facility |
First Name: | Core |
Address: | M32, SIMR, College of Pharmacy, Health Sciences, University of Sharjah |
Email: | tims-tof@sharjah.ac.ae |
Phone: | 065057656 |
Summary of all studies in project PR001810
Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
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ST002910 | Identifying the impact of RelA overexpression in triple negative breast cancer cells using mass spectroscopy-based proteomics and metabolomics analysis | Homo sapiens | Sharjah Institute for Medical Research | MS | 2024-04-05 | 1 | 12 | Uploaded data (4.5G)* |