Summary of project PR001822
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001822. The data can be accessed directly via it's Project DOI: 10.21228/M86H8Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001822 |
| Project DOI: | doi: 10.21228/M86H8Z |
| Project Title: | Role of hypoxia inducible factor-1a (HIF1a) in Skeletal Muscle Physiology |
| Project Summary: | Hypoxia-inducible factor (HIF)-1a is continuously synthesized and degraded in normoxia, whereas during hypoxia, HIF1a stabilization restricts cellular oxygen utilization. Less is known about HIF1a function(s) and sex-specific effects during normoxia in the basal state. Since skeletal muscle is the largest protein store in mammals and protein homeostasis has high energy demands, we determined HIF1a function at baseline during normoxia in skeletal muscle with the use of untargeted metabolomics. |
| Institute: | Cleveland Clinic |
| Department: | Inflammation and Immunity |
| Last Name: | Dasarathy |
| First Name: | Srinivasan |
| Address: | 9500 Euclid Avenue |
| Email: | dasaras@ccf.org |
| Phone: | 2163799846 |
| Funding Source: | NIH |
Summary of all studies in project PR001822
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002929 | Hypoxia-inducible factor-1a (HIF1a) physiology in mouse skeletal muscle | Mus musculus | Cleveland Clinic | MS* | 2024-10-28 | 1 | 96 | Uploaded data (1.6G)* |
| ST002930 | Role of Hypoxia-inducible factor-1a (HIF1a)in Skeletal Muscle Physiology (C2C12 myotube model) | Mus musculus | Cleveland Clinic | MS* | 2024-10-28 | 1 | 30 | Uploaded data (1.6G)* |
