Summary of project PR001830
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001830. The data can be accessed directly via it's Project DOI: 10.21228/M85H91 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001830 |
| Project DOI: | doi: 10.21228/M85H91 |
| Project Title: | Targeted analyses of microbial metabolism for the XMaS clinical trial |
| Project Summary: | The Xanthohumol microbiome and signature (XMaS) study in healthy adults was a phase I, triple-masked, placebo-controlled clinical trial in healthy adults investigating effects of a natural product supplement of gut microbiome composition and metabolism. Xanthohumol, a flavonoid from the hops plant or placebo was administered to 27 healthy adults daily for eight weeks. Fecal, plasma, and 24-hr urine collections were obtained from participants at baseline and 2-week intervals. The main objective was to examine clinical safety and subjective tolerability of xanthohumol compared to placebo. Additional aims were to monitor biomarkers of inflammation, gut permeability, bile acid metabolism, short-chain fatty acids, and metabolism of xanthohumol. |
| Institute: | Oregon State University |
| Last Name: | Jamieson |
| First Name: | Paige |
| Address: | 307 LINUS PAULING SCIENCE CTR |
| Email: | jamiesop@oregonstate.edu |
| Phone: | 5417379804 |
Summary of all studies in project PR001830
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002941 | Targeted analyses of microbial metabolites of xanthohumol | Homo sapiens | Oregon State University | MS | 2024-01-01 | 1 | 135 | Not available |
| ST002942 | Targeted analysis of short chain fatty acids for the XMaS clinical trial. | Homo sapiens | Oregon State University | MS | 2024-01-01 | 1 | 135 | Not available |
| ST002943 | Targeted bile acid analysis for the XMaS trial. | Homo sapiens | Oregon State University | MS | 2024-01-01 | 1 | 135 | Not available |
