Summary of project PR001884
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001884. The data can be accessed directly via it's Project DOI: 10.21228/M8672X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001884 |
| Project DOI: | doi: 10.21228/M8672X |
| Project Title: | Early time-restricted eating improves markers of cardiometabolic health but has no impact on nutrient absorption in healthy adults |
| Project Type: | Randomized Controlled Trial |
| Project Summary: | Early time-restricted eating (eTRE) improves aspects of cardiometabolic health. Although the circadian system appears to regulate nutrient absorption, little is known about the effects of eTRE on intestinal absorption. In this randomized crossover trial, 16 healthy adults follow a controlled, weight-maintenance diet for 9 days consuming all calories between 0800 and 1400 (eTRE schedule) or 0800 and 2000 (control schedule). We measure the energy content of the diet, stool, and urine with bomb calorimetry and calculate intestinal energy absorption. The eTRE schedule is more effective than the control eating schedule for improving markers of cardiometabolic health, including 24-h mean glucose concentrations and glycemic variability, assessed as the mean amplitude of glycemic excursions. However, eTRE has no effect on intestinal energy and macronutrient absorption, gastrointestinal transit time, colonic hydrogen gas production, or stool microbial composition, suggesting eTRE does not impact gastrointestinal function. |
| Institute: | Pennington Biomedical Research Center |
| Department: | Clinical Sciences |
| Last Name: | Berryman |
| First Name: | Claire |
| Address: | 6400 Perkins Road, Baton Rouge, LA 70808 |
| Email: | claire.berryman@pbrc.edu |
| Phone: | (225) 763-3010 |
Summary of all studies in project PR001884
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003031 | Early time-restricted eating improves markers of cardiometabolic health but has no impact on nutrient absorption in healthy adults | Homo sapiens | California Polytechnic State University, San Luis Obispo | MS | 2024-01-23 | 1 | 88 | Uploaded data (7.9M)* |
