Summary of project PR001949
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001949. The data can be accessed directly via it's Project DOI: 10.21228/M8SM7W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001949 |
| Project DOI: | doi: 10.21228/M8SM7W |
| Project Title: | Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock |
| Project Summary: | The aim of this study was to identify circulating markers that correlated with severity and mortality in sepsis. We performed metabolomic profiling on 4 cohorts: 1) patients with septic shock, 2) patients with bacteremia without sepsis, 3) cardiogenic shock, and 4) healthy ambulatory controls. We found a set of metabolites that out outperformed lactate in their ability to distinguish survivors and non-survivors of sepsis. |
| Institute: | Massachusetts General Hospital |
| Department: | Molecular Biology |
| Laboratory: | Mootha Laboratory |
| Last Name: | Sharma |
| First Name: | Rohit |
| Address: | 185 Cambridge Street, 6th Floor, Boston, MA, 02114, USA |
| Email: | rsharma2@partners.org |
| Phone: | (617) 643-3059 |
Summary of all studies in project PR001949
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003136 | Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock | Homo sapiens | Massachusetts General Hospital | MS | 2025-01-05 | 1 | 98 | Uploaded data (1.3G)* |
