Summary of project PR001951
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001951. The data can be accessed directly via it's Project DOI: 10.21228/M8J43C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001951 |
| Project DOI: | doi: 10.21228/M8J43C |
| Project Title: | Endothelial-Dependent Vascular Reactivity After Cardiopulmonary Bypass is Associated with Unique Metabolomic Signatures |
| Project Type: | Untargeted Metabolomics analysis |
| Project Summary: | Cardiopulmonary bypass (CPB), an extracorporeal method necessary for the surgical correction of complex congenital heart defects, incites significant inflammatory and vascular changes. Along with these changes are alterations in cellular metabolism that promote energy production to deal with this stress. Utilizing laser-doppler perfusion monitoring coupled with iontophoresis (LDPMI) in patients undergoing corrective heart surgery, we hypothesized that temporal, untargeted metabolomics could be performed to assess the link between metabolism and vascular function. The data give insight into the metabolic landscape of children undergoing CPB for corrective heart surgery and provide detail into how these metabolites relate to physiological aberrations in the vasculature. |
| Institute: | Vanderbilt University |
| Department: | Chemistry |
| Laboratory: | Center for Innovative Technology |
| Last Name: | CODREANU |
| First Name: | SIMONA |
| Address: | 1234 STEVENSON CENTER LANE |
| Email: | SIMONA.CODREANU@VANDERBILT.EDU |
| Phone: | 6158758422 |
Summary of all studies in project PR001951
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003139 | Endothelial-Dependent Vascular Reactivity After Cardiopulmonary Bypass is Associated with Unique Metabolomic Signatures | Homo sapiens | Vanderbilt University | MS* | 2024-09-23 | 1 | 36 | Uploaded data (15.9G)* |
