Summary of project PR002003
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002003. The data can be accessed directly via it's Project DOI: 10.21228/M8Q237 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002003 |
| Project DOI: | doi: 10.21228/M8Q237 |
| Project Title: | Honeybee metabolomics 2022 for Understanding Honeybee Toxicity |
| Project Type: | Untargeted metabolomics |
| Project Summary: | The impact of crop protection products on pollinating insects, particularly honeybees, is a critical consideration for ecological safety. Beyond acute toxicity, sublethal effects can potentially disrupt honeybee behavior, compromising pollination efficiency. Traditional assessment methods, reliant on visual observations, may not be optimal for capturing sublethal effects. In this study, we delved into molecular mechanisms underlying sublethal effects, employing three distinct platforms: whole-tissue transcriptomics, spatial transcriptomics, and metabolomics. Our findings reveal valuable insights into honeybee toxicity, with certain approaches demonstrating superiority in elucidating tissue-specific and treatment-specific responses, especially untargeted metabolomics tend to be a valuable tool for new bee-friendly agrochemical development. This research will aid in screening new molecules for pollinator safety and contribute to developing strategies that enhance crop yield while maintaining ecological sustainability. |
| Institute: | Corteva Agriscience |
| Last Name: | Yang |
| First Name: | Kundi |
| Address: | 9330 Zionsville Rd, Indianapolis, IN 46268, Indianapolis, Indiana, 46077, USA |
| Email: | kundi.yang@corteva.com |
| Phone: | 5133063039 |
Summary of all studies in project PR002003
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003212 | Using Untargeted Metabolomics as a New Approach for Understanding Honeybee Toxicity | Apis mellifera | Corteva Agriscience | MS* | 2024-12-30 | 1 | 20 | Uploaded data (7.4G)* |
