Summary of project PR002012
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002012. The data can be accessed directly via it's Project DOI: 10.21228/M8J82C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002012 |
| Project DOI: | doi: 10.21228/M8J82C |
| Project Title: | Plasma metabolomics of patients diagnosed with Alzheimer's Disease under Acetylcholinesterase Inhibitors treatment |
| Project Type: | Untargeted Lipidomics |
| Project Summary: | Alzheimer’s Disease (AD) is a fatal neurodegenerative disorder characterized by progressive memory loss, loss of cognitive capacity, mood swings, communication and rationality impairment and eventual loss of independent living. There is still no cure for this disease, but some medicine can delay the progression of symptoms and improve patients’ life quality by acting in the reduction of symptom severity. Acetylcholinesterase inhibitors (AChI) are the main class of drug employed for this. In this context, this research has a goal of evaluating the metabolomic and lipidomic profile of sanguine plasma of patients diagnosed with AD before and after the use of AChI to elucidate metabolic alterations that can assist the diagnosis and contribute to the literature. |
| Institute: | State University of Campinas (UNICAMP) |
| Department: | Institute of Chemistry |
| Laboratory: | Laboratory of Bioanalytics and Integated Omics (LaBIOmics) |
| Last Name: | Marques |
| First Name: | Mariana |
| Address: | Rua Josué de Castro, s/n, Campinas, São Paulo, 13083-862, Brazil |
| Email: | mari31marques@gmail.com |
| Phone: | +55 19 35213038 |
| Funding Source: | Conselho Nacional de Desenvolvimento Científico e Tecnólogico |
| Contributors: | Alessandra Sussulini, Leda Leme Talib, Wagner Farid Gattaz |
Summary of all studies in project PR002012
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003237 | Plasma metabolomics of patients diagnosed with Alzheimer's Disease under Acetylcholinesterase Inhibitors treatment | Homo sapiens | University of Campinas | MS* | 2025-06-24 | 1 | 83 | Uploaded data (17.2M)* |
