Summary of project PR002030
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002030. The data can be accessed directly via it's Project DOI: 10.21228/M86V58 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002030 |
| Project DOI: | doi: 10.21228/M86V58 |
| Project Title: | Metabolomic changes in mouse tissues following modulation of serine through the diet |
| Project Summary: | We analyzed metabolites in the retina, choroid/RPE, and plasma from WT and PHGDH heterozygous mice that were fed either a control or serine/glycine-deprived diet. Additionally, we also analyzed metabolites from the retina, choroid/RPE, paw skin, and plasma from mice that were previously on either a control or serine/glycine-deprived diet and then switched back to a control or serine-supplemented diet. |
| Institute: | Salk Institute |
| Department: | Molecular and Cell Biology Laboratory |
| Laboratory: | Metallo Lab |
| Last Name: | Lim |
| First Name: | Esther |
| Address: | 10010 N Torrey Pines Rd, La Jolla, CA, 92037, USA |
| Email: | ewlim2024@gmail.com |
| Phone: | (858) 453-4100 |
| Funding Source: | R01CA234245 |
Summary of all studies in project PR002030
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003268 | WT and PHGDH(+/-) mice fed control or -SG diet: Plasma | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 21 | Uploaded data (215.4M)* |
| ST003269 | WT and PHGDH(+/-) mice fed control or -SG diet: Retina samples | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 20 | Uploaded data (204.8M)* |
| ST003270 | WT and PHGDH(+/-) mice fed control or -SG diet: Back of eye | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 20 | Uploaded data (204.6M)* |
| ST003271 | Impact of serine supplementation following treatment with serine/glycine-depleted diet: Paw skin | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 20 | Uploaded data (183.9M)* |
| ST003272 | Impact of serine supplementation following treatment with serine/glycine-depleted diet: Retina and back of eye samples | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 40 | Uploaded data (369.2M)* |
| ST003273 | Impact of serine supplementation following treatment with serine/glycine-depleted diet: Plasma | Mus musculus | Salk Institute for Biological Studies | MS | 2024-07-10 | 1 | 20 | Uploaded data (365.7M)* |
