Summary of project PR002048

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002048. The data can be accessed directly via it's Project DOI: 10.21228/M8WG0S This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR002048
Project DOI:doi: 10.21228/M8WG0S
Project Title:Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1.
Project Summary:Recent evidence suggests that PD-L1, well-known as the ligand of the immune inhibitory receptor PD-1, can have cell-intrinsic effects in cancer and immune cells. One such cell-intrinsic effect is modulation of cellular metabolism, including regulation of mTOR activity and glycolysis. Here, we analyzed the metabolome of cultured mouse prostate cancer cells (TRAMP-C2) expressing PD-L1 or with PD-L1 deleted via CRISPR/Cas9.
Institute:University of Ottawa
Last Name:Hodgins
First Name:Jonathan
Address:451 Smyth Rd, Ottawa, Ontario, K1H 8M5, Canada
Email:jonathanhodgins17@gmail.com
Phone:613-562-5800

Summary of all studies in project PR002048

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
Release
Date
VersionSamplesDownload
(* : Contains raw data)
ST003297 Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1. Mus musculus University of Ottawa MS 2024-07-28 1 75 Uploaded data (2.3G)*
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