Summary of project PR002048
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002048. The data can be accessed directly via it's Project DOI: 10.21228/M8WG0S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Project ID: | PR002048 |
Project DOI: | doi: 10.21228/M8WG0S |
Project Title: | Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1. |
Project Summary: | Recent evidence suggests that PD-L1, well-known as the ligand of the immune inhibitory receptor PD-1, can have cell-intrinsic effects in cancer and immune cells. One such cell-intrinsic effect is modulation of cellular metabolism, including regulation of mTOR activity and glycolysis. Here, we analyzed the metabolome of cultured mouse prostate cancer cells (TRAMP-C2) expressing PD-L1 or with PD-L1 deleted via CRISPR/Cas9. |
Institute: | University of Ottawa |
Last Name: | Hodgins |
First Name: | Jonathan |
Address: | 451 Smyth Rd, Ottawa, Ontario, K1H 8M5, Canada |
Email: | jonathanhodgins17@gmail.com |
Phone: | 613-562-5800 |
Summary of all studies in project PR002048
Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
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ST003297 | Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1. | Mus musculus | University of Ottawa | MS | 2024-07-28 | 1 | 75 | Uploaded data (2.3G)* |