Summary of project PR002087
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002087. The data can be accessed directly via it's Project DOI: 10.21228/M8V825 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002087 |
| Project DOI: | doi: 10.21228/M8V825 |
| Project Title: | Bile acid–induced gut mitochondrial dysfunction promotes Enterobacteriaceae colonization and associates with dysbiosis in Crohn's disease |
| Project Summary: | Members of the Enterobacteriaceae family of bacteria are often overrepresented in inflammatory bowel disease (IBD). Bile acids (BAs) are cholesterol derivatives that are known to affect the growth of potentially pathogenic commensals (pathobionts), including those from the Enterobacteriaceae family. Furthermore, BAs are often increased in the colonic lumen of IBD patients, including patients with Crohn’s disease (CD). Here, we investigated whether bile acids influence gut colonization by Enterobacteriaceae. |
| Institute: | University of British Columbia |
| Last Name: | Finlay |
| First Name: | Brett |
| Address: | office: MSL 333 lab: MSL 363 |
| Email: | bfinlay@interchange.ubc.ca |
| Phone: | 604-822-2210 |
| Funding Source: | Canadian Institutes of Health Research (CIHR) [FDN-159935] and Genome Canada/Genome BC (264PRO) |
Summary of all studies in project PR002087
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003361 | Bile acid–induced gut mitochondrial dysfunction promotes Enterobacteriaceae colonization and associates with dysbiosis in Crohn's disease | Mus musculus | University of British Columbia | MS | 2024-08-05 | 1 | 48 | Uploaded data (5.2G)* |
