Summary of project PR002090
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002090. The data can be accessed directly via it's Project DOI: 10.21228/M8G24F This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002090 |
| Project DOI: | doi: 10.21228/M8G24F |
| Project Title: | Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in fibro-calcific aortic valve disease |
| Project Summary: | In-depth lipidomics profiling was performed on human tricuspid and bicuspid aortic valve tissue at different pathological stages, including mildly diseased, fibrotic and calcific tissue sections. Untargeted and targeted analysis were employed to enable high identification coverage and accurate quantification of lipids. Chromatographic separation modes (C18 RPC, C30 RPC) was combined with MS analysis using various acquisition modes (full MS, DDA, SRM) to allow for the identification of 1084 lipid molecular species across 28 lipid subclasses, of which 480 lipids were semi-absolutely quantified. |
| Institute: | Technical University Dresden |
| Last Name: | Fedorova |
| First Name: | Maria |
| Address: | Tatzberg 47/49, Dresden, Saxony, 01307, Germany |
| Email: | maria.fedorova@tu-dresden.de |
| Phone: | +49 351 796 36617 |
Summary of all studies in project PR002090
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003364 | Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in fibro-calcific aortic valve disease | Homo sapiens | Technical University Dresden | MS | 2024-08-15 | 1 | 431 | Uploaded data (233.6G)* |
