Summary of project PR002101
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002101. The data can be accessed directly via it's Project DOI: 10.21228/M81V7G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002101 |
| Project DOI: | doi: 10.21228/M81V7G |
| Project Title: | In-depth profiling of biosignatures for Type 2 diabetes mellitus cohort utilizing an integrated targeted LC-MS platform |
| Project Type: | Observational study |
| Project Summary: | We proposed an optimized and in-depth target-based metabolome platform through an integration of six distinct conditions, including a normal phase principle, a pre-column chemical derivatization, as well as four reversed phase separation methods for the absolute quantification and profiling of a total of 1609 small molecules (32 sub-classes) in serum after normalization using isotope labeled internal standards. Herein, we present a new dataset of a metabolomic profiles encompassing a cohort of 200 healthy individuals and 100 newly diagnosed Type 2 diabetes mellitus patients from the northern region of China. We hereby make these technical validation results and the profiling dataset publicly available to the scientific community, showcasing its exceptional sensitivity and robustness as an invaluable tool for metabolome analysis across laboratories. |
| Institute: | The First Affiliated Hospital of Dalian Medical University |
| Laboratory: | Laboratory of Integrative Medicine |
| Last Name: | Ma |
| First Name: | Shurong |
| Address: | No.222 Zhongshan Road, Xigang District, Dalian City, Liaoning Province, Dalian, Xigang District, Dalian City, Liaoning Province, 116000, China |
| Email: | mashurong@dmu.edu.cn |
| Phone: | +86-411-93635863 |
Summary of all studies in project PR002101
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003390 | In-depth profiling of biosignatures for Type 2 diabetes mellitus cohort utilizing an integrated targeted LC-MS platform | Homo sapiens | The First Affiliated Hospital of Dalian Medical University | MS | 2024-10-14 | 1 | 300 | Uploaded data (1.4G)* |
