Summary of project PR002268
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002268. The data can be accessed directly via it's Project DOI: 10.21228/M8G54G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002268 |
| Project DOI: | doi: 10.21228/M8G54G |
| Project Title: | Role of lipid-metabolizing enzyme PNPLA6 in retinal pigment epithelial cells and its mechanism of homeostasis |
| Project Summary: | PNPLA6 deficiency in the retina has been clinically reported to be a cause of retinitis pigmentosa, a disease leading to blindness. PNPLA6 is generally known to be an enzyme that degrades phospholipids in a calcium-independent manner, but its activity and substrates in the eye have not yet been elucidated. We focused on the function of PNPLA6, whose function in the retina is not well understood, and biochemically analyzed the mechanism by which retinal pigmentary degeneration occurs. |
| Institute: | University of Tokyo |
| Last Name: | Ono |
| First Name: | Takashi |
| Address: | 7-3-1, Hongo, Bunkyo-ku |
| Email: | taono-tky@umin.ac.jp |
| Phone: | +81-338155411 |
Summary of all studies in project PR002268
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003658 | Functional analysis of retinal pigment epithelial cells with PNPLA6 knockdown | Homo sapiens | University of Tokyo | MS | 2025-01-26 | 1 | 16 | Uploaded data (746.9K)* |
