Summary of project PR002374
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002374. The data can be accessed directly via it's Project DOI: 10.21228/M8RZ4W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002374 |
| Project DOI: | doi: 10.21228/M8RZ4W |
| Project Title: | Salivary Metabolome Profiling in Smokeless Tobacco Users. |
| Project Summary: | Objectives: The present study is conducted to investigate the biochemical and pathophysiological changes in saliva caused by smokeless tobacco (SLT) use relative to non-smokers. Materials and methods: Saliva samples collected from a total of 26 smokeless tobacco user, and 26 non-smoking control individuals were subjected to untargeted metabolomics analysis. Metabolites from the saliva samples of all the participants were analyzed and processed via MetaboScape software version 4 (Bruker, Darmstadt, Germany). Results: We identified 74 differentially abundant salivary metabolites in the comparisons between controls and smokeless tobacco (SLT) users. Among the 74 metabolites, 9 were significantly different in SLT users. Nutriacholic acid and elaidic acid were upregulated in SLT users. Conclusions: Salivary metabolomic profiling revealed distinct metabolic alterations in smokeless tobacco users compared to controls, highlighting potential biomarkers for metabolites detection and monitoring. |
| Institute: | Sharjah Institute for Medical Research |
| Last Name: | Facility |
| First Name: | Core |
| Address: | M32, SIMR, College of Pharmacy, Health Sciences, University of Sharjah |
| Email: | tims-tof@sharjah.ac.ae |
| Phone: | 065057656 |
Summary of all studies in project PR002374
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003800 | Salivary Metabolome Profiling in Smokeless Tobacco Users: A Comparative Study. | Homo sapiens | Sharjah Institute for Medical Research | MS | 2025-09-01 | 1 | 104 | Uploaded data (74.2G)* |
