Summary of project PR002382

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002382. The data can be accessed directly via it's Project DOI: 10.21228/M8QZ7Q This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR002382
Project DOI:doi: 10.21228/M8QZ7Q
Project Title:Lipidomics of human mammary epithelial stem-like cells (hMECs) overexpressing Glucose-6-phosphate dehydrogenase (G6PD)
Project Summary:Peroxisomes play a crucial role in cellular metabolism. Glucose-6-phosphate dehydrogenase (G6PD), the gatekeeper enzyme of the pentose phosphate pathway, is primarily localized in the cytosol. However, studies have reported its presence in peroxisomes as well. This project aims to determine the function of G6PD on the peroxisomal membrane. To investigate this, we overexpressed G6PD either in the cytosol or on the peroxisomal membrane of human mammary epithelial stem-like cells (hMECs), a cell line that retains characteristics of primary mammary epithelial stem cells, and analyzed their lipidomic profiles for comparison.
Institute:University of Helsinki
Department:Faculty of Biological and Environmental Sciences
Laboratory:Katajisto Laboratory
Last Name:Bui
First Name:Hien
Address:Biocenter 1, Viikinkaari 9, Helsinki, Uusimaa, 00790, Finland
Email:hien.bui@helsinki.fi
Phone:+358294159407

Summary of all studies in project PR002382

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST003808 Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division Homo sapiens University of Helsinki MS 2025-03-24 1 16 Uploaded data (23.7M)*
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